Constipation 101
What Are Laxatives?
Laxatives are commonly used medications for treating occasional constipation. They are available over the counter (OTC) and based on how they work, they can be categorized into osmotic agents, stimulants, bulk-forming agents and stool softeners.
Osmotic agents
Agents such as polyethylene glycol (PEG), lactulose and magnesium hydroxide are water-loving substances that attract and retain water in the colon to ease and enhance stool passage. Polyethylene glycol (found in RestoraLAX®) increases stool frequency and softness in individuals with constipation. It works with the water in your body to hydrate and soften stool, unblocking your bowel.
Stimulant laxatives
This type of laxative makes your body go by directly stimulating the nerves in your colon. This causes the muscles of the intestinal wall to contract and helps to push the stool along. This action can be effective for relieving occasional constipation. Senna and Bisacodyl are the most commonly used stimulant laxatives and are found in brands such as Senokot®, Ex-Lax® and Dulcolax®.
Bulk-forming agents
Bulk-forming agents are fibre supplements that trap water in the stool to increase stool weight and improve stool consistency. Commercially available fibre supplements include psyllium and bran. They may be appropriate for people who do not consume enough fibre in their diet. Some powder fibre supplements can be gritty and viscous when mixed into a beverage, which some people may find distasteful. Adequate fluid intake is necessary for bulk-forming agents to work; lack of water may enhance bloating. Bulk-forming brands include Benefibre® and Metamucil®.
Stool softeners
As the name suggests, stool softeners, such as docusate sodium, moisten and soften stool, making it easier to pass. They may work well for people with hard stools. Stool softener brands include Colace®.
References:
Jin J. JAMA. 2014;312:1167. Leung L et al. JAFBM. 2011;24:436-451. QuintilesIMS Survey 2018, Pharmacy Times Survey 2018, QuintilesIMS Survey 2018. Accessed September 14, 2017. DiPalma JA et al. South Med J. 2007;100:1085-1090. Cleveland MV et al. South Med J. 2001;94:478-481. DiPalma JA et al. Online J Dig Health. 1999;1:1-10.
RestoraLAX® Does Not Cause Bloating, Gas, Cramps
A Guide to Over-the-Counter Laxatives
A Helpful Guide from RestoraLAX®
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